Author

Whitney C. McFadden

Icahn School of Medicine at Mount SinaiORCID 0000-0002-1394-2131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Amanda L. DobbyniD· 3 shared Douglas M. RuderferiD· 3 shared Laura M. HuckinsiD· 3 shared Weiqing WangiD· 3 shared Eli A. StahliD· 2 shared Eric R. GamazoniD· 2 shared Hoang T. NguyeniD· 2 shared Menachem FromeriD· 2 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenetics

Amanda L. DobbynORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintNov 24, 2018

Integrative analysis of rare variants and pathway information shows convergent results between immune pathways, drug targets and epilepsy genes

Hoang T. Nguyen, Amanda L. Dobbyn, Alexander W. Charney…·Eli A. Stahl

The paper introduces a Bayesian framework to prioritize risk genes for complex diseases by integrating gene-set information with variant counts, identifying novel epilepsy risk genes and linking them to immune pathways and drug targets.

2 citations

humanwhole-exome sequencing

𝕏 PostBluesky

GeneticsbioRxivPreprintFeb 14, 2018

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

Laura M. Huckins, Amanda L. Dobbyn, Whitney C. McFadden…·Mario Maj

This paper uses transcriptomic imputation to identify gene-tissue associations linked to Anorexia Nervosa risk, finding significant links in both brain and metabolic tissues.

3 citations

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 21, 2017

Transcriptomic Imputation of Bipolar Disorder and Bipolar subtypes reveals 29 novel associated genes

Laura M. Huckins, Amanda L. Dobbyn, Whitney C. McFadden…·Eli A. Stahl

This study uses transcriptomic imputation to identify 29 novel genes associated with bipolar disorder and its subtypes, revealing biological pathways related to oxidative stress and circadian rhythms.

19 citations

humanbulk RNA-seq

𝕏 PostBluesky