Author

Takahisa Ikegami

Yokohama City UniversityORCID 0000-0002-1429-1844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Tsuyoshi KonumaiD· 3 shared Hideo AkutsuiD· 2 shared Ken‐ichi AkagiiD· 2 shared Satoko AkashiiD· 2 shared Yoko Motoda· 2 shared Aritaka Nagadoi· 1 shared Chieko Tsuchiya· 1 shared Eriko Chikaishi· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBiochemistry

Tsuyoshi KonumaORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 21, 2026

Fine-Tuning α-Synuclein Phase Separation through Sequence-Optimized Peptide Modulators

Tatsuya Ikenoue, Tsuyoshi Konuma, Takahisa Ikegami, Hiroaki Suga

This study develops a framework to design peptides that modulate α-synuclein phase separation by integrating deep mutational scanning and peptide screening.

DOI 10.64898/2026.02.21.707152

proteomicsdeep learning

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BiochemistryBiochemistryPeer-reviewedApr 21, 2025

Analysis of the high-order conformational changes in glyceraldehyde-3-phosphate dehydrogenase induced by nicotinamide adenine dinucleotide, adenosine triphosphate, and oxidants

Haruo Suzuki, Yuki Nicole Makiyama, Yuta Watanabe…·Takahisa Ikegami

This study investigates how NAD+, ATP, and oxidants induce conformational changes in GAPDH, revealing structural instability and subunit splitting under specific conditions.

4 citations

humanprotein structure

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BiochemistryProtein SciencePeer-reviewedMay 9, 2024

NMR analysis of the homodimeric structure of a D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria

Tsuyoshi Konuma, Tomoyo Takai, Chieko Tsuchiya…·Takahisa Ikegami

The paper determines the dimeric structure of VanX using NMR and identifies a monomeric form for inhibitor screening.

DOI 10.1002/pro.5002

protein structureexperimental assay

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