Serena Barral

This study compares in vivo and in vitro midbrain development to assess their similarity to human fetal tissue.

This paper identifies and prioritizes drug targets for major depressive disorder using genetic methods, finding that 82% of approved depression/anxiety drugs have significant genetic targets.

The paper establishes a humanized neuronal model to investigate the effects of manganese dysregulation on neuronal function and disease mechanisms.

This study identifies cardiac glycosides that restore autophagy and gene expression in an iPSC model of WDR45 deficiency, suggesting potential therapeutic applications for BPAN.