GenomicseLifePeer-reviewed
Free-living human cells reconfigure their chromosomes in the evolution back to uni-cellularity
Jin Xu, Xinxin Peng, Yuxin Chen…·Chung‐I Wu
The paper studies chromosomal evolution in cancer cell lines, finding that cells lose sex chromosomes and gain autosomes, leading to a 2:3 X:A ratio that may enhance fitness.
40 citations