Author

Stefano Coppola

The Netherlands Cancer InstituteORCID 0000-0002-1539-364XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Heta PateliD· 2 shared Tineke Laura LenstraiD· 2 shared Arwin GroenewoudiD· 1 shared Domenico LibriiD· 1 shared Ewa B. Snaar-JagalskaiD· 1 shared Gangyin ZhaoiD· 1 shared George Niklaus ThalmanniD· 1 shared Ineke BrouweriD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Heta PatelORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 28, 2023

Mechano-signaling of prostate tumor initiating cells facilitates their tropism to stiff metastatic niche

Lanpeng Chen, Gangyin Zhao, Marta De Menna…·Ewa B. Snaar-Jagalska

The paper shows that mechanotransduction via TAZ and cytoskeletal tension promotes prostate cancer stem cell metastasis and identifies a YAP/TAZ inhibitor as a potential therapeutic target.

DOI 10.1101/2023.08.28.553410

humanorganoid / primary culture

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Molecular BiologyMolecular CellPeer-reviewedMay 1, 2023

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes

Heta Patel, Stefano Coppola, Wim Pomp…·Tineke Laura Lenstra

The paper shows DNA supercoiling inhibits transcriptional bursting of neighboring genes in yeast, differing from bacterial mechanisms.

63 citationstop 2%

yeastexperimental assay

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Systems BiologyeLifePeer-reviewedOct 17, 2022

Quantifying how post-transcriptional noise and gene copy number variation bias transcriptional parameter inference from mRNA distributions

Xiaoming Fu, Heta Patel, Stefano Coppola…·Ramon Grima

48 citations

yeastbulk RNA-seq

𝕏 PostBluesky