Author

Toshirou Nishida

National Cancer Center HospitalORCID 0000-0002-1542-6317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

Isamu ShiinaiD· 2 shared Miyuki Natsume· 2 shared Yuuki ObataiD· 2 shared Daiki UsukuraiD· 1 shared Hisazumi TsutsuiiD· 1 shared Mariko Niwa· 1 shared Motoyuki Shimonaka· 1 shared Ryo AbeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Isamu ShiinaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyScientific ReportsPeer-reviewedAug 6, 2025

Golgi retention of KIT in gastrointestinal stromal tumour cells is phospholipase D activity-dependent

Yuuki Obata, Miyuki Natsume, Isamu Shiina…·Toshirou Nishida

This study shows that KIT mutant retention in the Golgi/TGN in GISTs depends on the PLCγ2-PKD2-PLD2 pathway, leading to signal inactivation upon PLD inhibition.

DOI 10.1038/s41598-025-14739-w

humanexperimental assay

𝕏 PostBluesky

Cell BiologyJournal of Biological ChemistryPeer-reviewedApr 26, 2024

Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5

Miyuki Natsume, Mariko Niwa, Sho Ichikawa…·Yuuki Obata

This study shows that BFA and M-COPA inhibit RTK export from the ER by inactivating ARF1, ARF4, and ARF5, leading to cancer cell apoptosis.

7 citations

humanproteomics

𝕏 PostBluesky