Cancer BiologybioRxivPreprint
Tuning the Structural Properties of a Single-Domain Antibody Scaffold for Improved Fibroblast Activation Protein Targeting
Kendahl L. Ott, Joseph P. Gallant, Ohyun Kwon…·Aaron Matthew LeBeau
This study engineers single-domain antibodies to improve targeting of FAP, showing that valency and molecular weight affect tumor uptake and biodistribution.
DOI 10.64898/2026.03.11.711127