biHash: bisulfite-aware recursive nucleotide hashing
biHash is a rolling hash algorithm designed for bisulfite-sequenced data, offering faster hashing by recognizing bisulfite-compatible sequence states.
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BC Cancer AgencyORCID 0000-0002-1687-8972Unclaimed ORCID profile · follow to get notified of new preprints
9 papers
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biHash is a rolling hash algorithm designed for bisulfite-sequenced data, offering faster hashing by recognizing bisulfite-compatible sequence states.
Johnathan Wong, Lauren Coombe, René L. Warren, İnanç Birol
aaKomp provides a fast, memory-efficient, alignment-free method for genome completeness assessment, outperforming existing tools in speed and scalability.
Lauren Coombe, Parham Kazemi, Johnathan Wong…·René L. Warren
The paper introduces ntSynt, a tool for detecting multi-genome synteny blocks using minimizer graphs, showing high coverage and efficiency across diverse genomes.
Emily Rong Zhang, Lauren Coombe, Johnathan Wong…·İnanç Birol
GoldPolish-Target polishes targeted regions of genome assemblies, reducing errors and improving accuracy with lower computational demands.
René L. Warren, Lauren Coombe, Johnathan Wong…·İnanç Birol
ntRoot infers human super-population ancestry from genomic data with high accuracy and efficiency, outperforming traditional methods on large datasets.
Johnathan Wong, Lauren Coombe, Vladimir Nikolić…·İnanç Birol
GoldRush is a de novo long read genome assembler with linear time complexity, achieving efficient assembly of large genomes with high contiguity and low memory usage.
Johnathan Wong, Parham Kazemi, Lauren Coombe…·İnanç Birol
aaHash is a recursive amino acid sequence hashing algorithm that improves speed and sensitivity for protein sequence analysis.
Lauren Coombe, Janet X. Li, Theodora Lo…·İnanç Birol
LongStitch improves draft genome assemblies using long reads, significantly increasing contiguity and accuracy compared to existing methods.
Zhuyi Xue, René L. Warren, Ewan A. Gibb…·İnanç Birol
The paper analyzes APA patterns in 114 cancer-related genes across 33 cancer types to show complex 3 UTR cleavage changes in tumors.