Author

Ivan V. Zvyagin

Russian Academy of SciencesORCID 0000-0002-1769-9116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Dmitriy M. ChudakoviD· 2 shared Mikhail ShugayiD· 2 shared Vadim K KarnaukhoviD· 2 shared Annalisa NicastriiD· 1 shared D. N. Scherbinin· 1 shared Dmitrii S. Shcherbinin· 1 shared Hashem KoohyiD· 1 shared Isaac B. WoodhouseiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Dmitriy M. ChudakovORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 29, 2023

Abundance of human T-cell epitopes in microbial proteomes

Vasilisa A. Kovaleva, Ivan V. Zvyagin

The paper analyzes the prevalence of human T-cell epitopes in microbial proteomes, finding significant overlap with HLA-I and HLA-II ligands, suggesting potential pro-inflammatory effects of molecular mimicry.

DOI 10.1101/2023.11.29.568792

humanproteomics

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BioinformaticsFrontiers in ImmunologyPeer-reviewedAug 15, 2023

Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features.

Dmitrii S. Shcherbinin, Vadim K Karnaukhov, Ivan V. Zvyagin…·Mikhail Shugay

The paper uses template-based modeling to generate TCR:antigen:MHC structures and identifies amino acid contact features that influence antigen recognition.

7 citations

protein structureexperimental assay

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BioinformaticsbioRxivPreprintFeb 16, 2021

HLA binding of self-peptides is biased towards proteins with specific molecular functions

Vadim K Karnaukhov, Wayne Paes, Isaac B. Woodhouse…·Mikhail Shugay

The paper shows HLA alleles preferentially present peptides from proteins with specific molecular functions, linking these preferences to HLA allele differences and disease susceptibility.

8 citations

humanproteomics

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