Cell BiologybioRxivPreprint
Vascularized Human Cardiac Organoids Reveal Endothelial-Cardiomyocyte Crosstalk and Mechanisms of Carfilzomib-Induced Cardiotoxicity
Yuan Yang, Liyang Zhao, Honglin Tao…·Joe Z. Zhang
This study creates vascularized human cardiac organoids to study endothelial-cardiomyocyte interactions and cardiotoxicity mechanisms, finding bidirectional crosstalk and ER stress pathways involved in drug toxicity.