Author

Midhun K. Madhu

Indian Institute of Science Education and Research, BhopalORCID 0000-0002-1787-7920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Approach:graph neural network· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rajesh K. MurarkaiD· 2 shared Kunal ShewaniiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Rajesh K. MurarkaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 29, 2025

Mechanistic basis for GPCR phosphorylation-dependent allosteric signaling specificity of β-arrestin 1 and 2

Midhun K. Madhu, Rajesh K. Murarka

This study maps how phosphorylation patterns shape β-arrestin structure and function using simulations and machine learning, revealing isoform-specific allosteric responses and effector engagement.

DOI 10.1101/2025.04.29.649777

deep learninggraph neural network

𝕏 PostBluesky

BiophysicsBiophysical ChemistryPeer-reviewedApr 5, 2024

Mechanistic Insights into G-protein Activation via Phosphorylation Mediated Non-Canonical Pathway

Kunal Shewani, Midhun K. Madhu, Rajesh K. Murarka

This study identifies how RTK phosphorylations induce G-protein activation through structural changes and faster GDP release.

DOI 10.1016/j.bpc.2024.107234

proteomicsdeep learning

𝕏 PostBluesky