Coalescent theory of the {psi} directionality index
This paper develops theoretical predictions for the directionality index in coalescent models of two populations and analyzes its behavior in Drosophila melanogaster.
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Stanford UniversityORCID 0000-0002-1829-8664Unclaimed ORCID profile · follow to get notified of new preprints
17 papers
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This paper develops theoretical predictions for the directionality index in coalescent models of two populations and analyzes its behavior in Drosophila melanogaster.
Xiran Liu, Zarif Ahsan, Noah A. Rosenberg
The paper mathematically analyzes bounds on allele-sharing dissimilarity (ASD) statistics, showing how expected ASD values are constrained by allele frequencies, explaining narrow empirical ranges observed in human populations.
Maike L. Morrison, Katherine S. Xue, Noah A. Rosenberg
FAVA quantifies compositional variability across multiple microbiome samples using a normalized index, enabling comparison of taxonomic or functional relative abundances across different conditions and sample numbers.
The paper evaluates using SNP data from poor-quality DNA to match STR profiles, showing similar accuracy to full-genome data with 5-10% coverage.
Romain Laurent, Zachary A. Szpiech, Sergio S. da Costa…·Paul Verdu
This study analyzes genetic and linguistic data from Cabo Verde to trace admixture histories, finding early European-African mixing predating the Trans-Atlantic Slave Trade and ongoing effects of socio-cultural dynamics.
Daniel J. Cotter, Alissa L. Severson, Shai Carmi, Noah A. Rosenberg
The paper derives the limiting distribution of X-chromosomal coalescence times under first-cousin consanguineous mating, showing different effects based on consanguinity type.
The paper provides Taylor approximations for expected values and variances of ratios of tree properties under the coalescent, showing good agreement with simulations for expectations but less so for variances.
Nicolas Alcala, Noah A. Rosenberg
The paper derives mathematical constraints on FST for multiallelic markers across multiple populations and applies them to explain microsatellite differentiation patterns.
Alissa L. Severson, Shai Carmi, Noah A. Rosenberg
The paper derives the variance and limiting distribution of coalescence times in a diploid consanguineous population model, showing scaling behavior similar to a standard coalescent.
Simina Maria Boca, Lucy Huang, Noah A. Rosenberg
The paper derives a relationship between heterozygosity and admixture proportions in admixed populations, showing that heterozygosity is at least as high as the least heterozygous source population.
Alyssa Lyn Fortier, Jaehee Kim, Noah A. Rosenberg
This paper demonstrates that using ancestry inference on query profiles can reduce false-positive rates in familial searching by avoiding extreme allele-frequency misspecifications.
Gili Greenbaum, Amir Rubin, Alan R. Templeton, Noah A. Rosenberg
The paper introduces a network-based method for analyzing population structure in genomic data, demonstrating its application in Arabidopsis thaliana and human populations.
Nicolas Alcala, Amy Goldberg, Uma Ramakrishnan, Noah A. Rosenberg
The paper uses coalescent theory to analyze migration network motifs and their impact on genetic diversity and differentiation in small population networks.
Trevor J. Pemberton, Paul Verdu, Noémie S. Becker…·Évelyne Heyer
The paper identifies genetic associations with body size traits in Central African Pygmies and non-Pygmies using SNP data from a modest sample size.
Jaehee Kim, Michael D. Edge, Bridget F. B. Algee-Hewitt…·Noah A. Rosenberg
The paper shows linkage disequilibrium can identify relatives using nonoverlapping genetic markers, with 30-36% accuracy for parent-offspring and sib pairs.
Amy Goldberg, Torsten Günther, Noah A. Rosenberg, Mattias Jakobsson
The paper responds to criticism of male-biased admixture estimates from Bronze Age migrations by analyzing X-chromosomal and autosomal ancestry in ancient samples.
Nicolas Alcala, Noah A. Rosenberg
The paper analyzes mathematical constraints on FST for multiple populations, showing how FST depends on allele frequency and subpopulation number, and applies findings to human genetic data.