Marina Barba‐Aliaga

This study shows that eIF5A facilitates efficient translation of high codon-optimal chaperones under heat stress, enhancing proteostasis and heat resistance in yeast.

This study shows eIF5A coordinates gene expression by repressing transcription of its target genes in the nucleus while promoting their translation in the cytoplasm.

This study shows eIF5A alleviates ribosome stalling at TIM50 mRNA, enabling mitochondrial protein import and oxidative phosphorylation.

This study shows that hypusinated eIF5A is essential for collagen translation, with depletion leading to reduced collagen levels and ER stress in mouse fibroblasts and human hepatic stellate cells.

The paper shows that cell volume regulates rDNA copy number and RNA polymerase I synthesis rate in yeast through a feedback mechanism involving Sir2.