Synthetic BiologyProceedings of the National Academy of SciencesPeer-reviewed
Directed Evolution of Genetically Encoded LYTACs for Cell-Mediated Delivery
Jonathan Lee Yang, Sean A. Yamada‐Hunter, Louai Labanieh…·Alice Y. Ting
The paper describes the development of genetically encodable LYTACs (GELYTACs) for targeted protein degradation using engineered T-cells, showing efficacy in secreting and delivering the therapeutics.
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