Aaron M. Fleming

This study uses single-molecule nanopore sequencing to analyze rRNA modifications in human cells, revealing local coordination of modifications and their response to drug treatment.

This study uses nanopore sequencing to identify operon-specific ribosome remodeling in Staphylococcus aureus resistant to naphthyridone antibiotics.

This study maps oxidative and nitrosative damage to ribosomal RNA in human cells under stress, revealing distinct damage patterns in cytosolic and mitochondrial ribosomes.

The paper shows CO2 protects cells from iron-Fenton oxidative DNA damage by generating carbonate radical anion, leading to guanine oxidation in both E. coli and humans.

This study investigates how DNA damage affects the folding kinetics of G-quadruplex sequences in a DGD motif, showing accelerated folding with specific damage types and locations.

This study identifies APE1 as an RNA G-quadruplex binding protein that regulates miR-92b expression by modulating rG4 structure folding and miRNA maturation in cancer cells.