Author

Keisha N. Hardeman

Vanderbilt UniversityORCID 0000-0002-2032-7399Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

B. Bishal PaudeliD· 2 shared Corey E. HayfordiD· 2 shared Vito QuarantaiD· 2 shared Charles T. RobbinsiD· 1 shared Dongya JiaiD· 1 shared Herbert LevineiD· 1 shared JOHN A. JUN. MCLEANiD· 1 shared José N. OnuchiciD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

B. Bishal PaudelORCID

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2 papers

Recent·Most cited

Systems BiologyFrontiers in OncologyPeer-reviewedAug 14, 2020

Drug-tolerant idling melanoma cells exhibit theory-predicted metabolic low-low phenotype

Dongya Jia, B. Bishal Paudel, Corey E. Hayford…·Vito Quaranta

The paper identifies a drug-tolerant metabolic state in melanoma cells that reduces both glycolysis and oxidative phosphorylation, supporting survival but limiting growth.

24 citations

humanbulk RNA-seq

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Systems BiologybioRxivPreprintOct 28, 2019

Disruption of Redox Balance Enhances the Effects of BRAF-inhibition in Melanoma Cells

B. Bishal Paudel, Joshua E. Lewis, Keisha N. Hardeman…·Vito Quaranta

The paper shows that increased antioxidant capacity in BRAF-mutated melanoma cells reduces sensitivity to BRAF inhibitors and suggests targeting redox pathways could improve treatment outcomes.

4 citations

humanbulk RNA-seq

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