Dian Chen

This paper develops an automated imaging system for C. elegans behavior analysis and identifies serotonin's role in egg-laying and locomotion.

This paper introduces an image invariant-based method to measure C. elegans locomotor frequency without segmentation, showing improved robustness to low image quality and background noise.

This study investigates the conformational dynamics of the guanidine-IV riboswitch using single-molecule techniques, revealing its ligand-response mechanism and transcriptional sensitivity.