Marta Cascante

This study shows AML cells use extracellular protein catabolism to supply amino acids and manage nitrogen, with GS/GLUL playing a key role in ammonia buffering and disease progression.

This study shows that combining Palbociclib with Telaglenestat prevents acquired resistance in colorectal cancer cells by counteracting metabolic reprogramming.

This study shows that SARS-CoV-2's ORF9b protein activates inflammasomes and caspase-1, and small molecules inhibiting its homodimerization reduce inflammation and restore interferon signaling.

This study identifies mitochondrial and metabolic reprogramming induced by SARS-CoV-2 accessory proteins in lung cells, revealing potential therapeutic targets.

The paper introduces a microservices-based framework for scalable data analysis, validated in metabolomics, enabling dynamic scaling and integration of software tools.

PhenoMeNal provides a cloud-based platform for metabolomics data analysis, integrating tools and workflows to enable reproducible and scalable research.