Arslan A. Zaidi

This study integrates genetic variation with plasma protein measurements in South Asians to identify pQTLs and build a proteogenomic disease network for understudied populations.

The paper investigates the relationship between mtDNA copy number and gene expression, finding they are largely decoupled and that mtDNA accessibility, not copy number, better explains expression variation.

The paper analyzes how SNP heritability estimates are affected by admixture and directional LD, showing biases in random-effect estimators and implications for GWAS and polygenic prediction.

The paper introduces a network-based method to analyze human genetic variation beyond continental groups, revealing complex relationships and challenging traditional clustering approaches.

This study investigates mtDNA copy number (mtCN) in a diverse cohort, finding ancestry-specific genetic and phenotypic associations and highlighting the impact of blood cell composition on results.

The paper shows that cousin marriage preferences increase long runs of homozygosity (ROH) in global populations by 1.5 times, but marriage practices explain only a small portion of ROH variation.

The paper introduces a high-throughput method for imaging and analyzing scalp hair morphology and validates a Python package for processing and measuring hair images.

This study shows that demographic history affects population stratification in polygenic scores, with recent structure being hard to correct using standard methods.

This paper introduces SUGIBS, a robust genome-wide ancestry inference method, and applies it to predict ancestry faces using the 1000 Genomes Project and facial imaging data.

The paper investigates mito-nuclear incompatibility in admixed populations, finding that mtDNA copy number decreases with increasing discordance between nuclear and mitochondrial ancestry.

The paper develops a population-genetic framework to model mitochondrial heteroplasmy inheritance and applies it to infer genetic drift and mutation rates during human development.