Molecular BiologybioRxivPreprint
Coenzyme A homeostasis regulates hypoxic signalling via UBFD1in triple-negative breast cancer
Paul Grevitt, Óscar Maiques, Kunal Shah…·Tyson V. Sharp
This study identifies CoAsy as a regulator of HIF signalling in TNBC, showing its loss stabilizes HIF-1 and HIF-2 and correlates with poor patient outcomes.
DOI 10.1101/2025.06.18.660436