Lawrence Corey

The paper uses long-read sequencing to study HIV transmission and population dynamics in acute infection, finding high multilineage transmission rates and rapid viral evolution.

The paper examines pre-HIV Th17 cell levels as predictors of early HIV disease progression, finding higher pre-infection Th17 frequencies correlate with faster CD4 decline.

The paper analyzes HIV breakthrough virus populations in antibody-mediated prevention trials, finding high rates of multilineage infections and recombination under VRC01 treatment.

This study identifies VRC01-mediated viral escape mutations in HIV-infected participants from antibody-mediated prevention trials, showing that VRC01 can select for escape variants with cross-resistance to other CD4bs bnAbs.

The paper identifies potent HSV antivirals using a 3D bioprinted human skin equivalent platform and evaluates cell-type specific antiviral efficacy.

This study identifies TIM-4-L as a novel target for T cell therapy in AML, showing engineered T cells effectively eliminate AML cells in vitro and in vivo.

The paper shows B cells and HSV-2-specific antibodies are present in skin during HSV-2 reactivation, with dynamic levels in tissue compared to serum.

The paper shows HSV-2 is controlled by cytokines from tissue-resident T cells, not direct cell killing, even when T-cell numbers are low.

This study finds that HIV-1 co-infection increases oral EBV shedding due to B cell activation and weakened cellular immune control, validated through mathematical modeling.