Author
Inova Health SystemORCID 0000-0002-2223-7944Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Brett Schroeder, Jae Choi, Alejandro A. Schäffer…·Anish Thomas
The paper identifies CLDN3 as a tumor-selective target in SCLC using proteogenomic analysis and validates its therapeutic potential with a monoclonal antibody.
Joshua P. Schaaf, Dave Mitchell, Jonathan D. Ogata…·Nicholas W. Bateman
ShapeUpLMD automates ROI optimization for laser microdissection, improving tumor purity and spatial accuracy in multi-omic tissue profiling.
Aswini Panigrahi, Allison L. Hunt, Diego M. Assis…·Radoslav Goldman
The paper uses laser microdissection and proteomics to compare tumor and stroma in HNSCC tissues, identifying ECM enrichment in stroma and potential targets for disease intervention.
Parth Anil Desai, Nobuyuki Takahashi, Rajesh Kumar…·Anish Thomas
This study maps the SCLC tumor microenvironment and identifies cancer-associated fibroblasts as key drivers of neuroendocrine state plasticity and poor prognosis.
Pang-ning Teng, Joshua P. Schaaf, Tamara S. Abulez…·Nicholas W. Bateman
ProteoMixture estimates cell type proportions in bulk tissue proteomics data using optimized protein signatures validated on high-grade serous ovarian cancer samples.