Genetic & Genomic MedicinemedRxivPreprint
Trans-ancestry polygenic models for the prediction of LDL blood levels: An analysis of the UK Biobank and Taiwan Biobank
Emadeldin Hassanin, Ko-Han Lee, Tzung‐Chien Hsieh…·Carlo Maj
This paper compares ancestry-specific and multi-ancestry polygenic risk scores for LDL prediction in East Asian populations using UK Biobank and Taiwan Biobank data, finding that multi-ancestry models are more generalizable.