Author

Mengyu Wu

Scripps Research InstituteORCID 0000-0002-2248-9383Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Benjamin BasantaiD· 2 shared Gabriel C. LanderiD· 2 shared Allison MakeriD· 1 shared Althea Hansel-HarrisiD· 1 shared Andrew J. BorstiD· 1 shared Brandon J. CourteauiD· 1 shared Brian LeeiD· 1 shared Carl Walkey· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Benjamin BasantaORCID

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3 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMay 19, 2026

Computational redesign of TALE proteins for DNA-templated assembly of protein fibers

Robbert J. de Haas, Mark D. Langowski, Andrew J. Borst…·Neil P. King

The paper redesigns TALE proteins to assemble linear protein-DNA complexes on double-stranded DNA templates, enabling controlled length and application in antigen display.

3 citations

DNA methylationexperimental assay

𝕏 PostBluesky

Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedJan 22, 2025

The conformational landscape of human transthyretin revealed by cryo-EM

Benjamin Basanta, Karina Nugroho, N. Yan…·Gabriel C. Lander

This study uses cryo-EM to reveal the conformational landscape of human transthyretin, uncovering asymmetries and new states relevant to ligand binding and amyloid formation.

26 citationstop 2%

humanprotein structure

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BiophysicsJournal of Structural BiologyPeer-reviewedJun 27, 2024

High-resolution single-particle imaging at 100-200 keV with the Gatan Alpine direct electron detector.

Lieza M. Chan, Brandon J. Courteau, Allison Maker…·Kliment A. Verba

This study evaluates the Gatan Alpine detector at 100-200 keV for cryo-EM, showing improved resolution and performance compared to the Gatan K3.

16 citations

cryo-EMexperimental assay

𝕏 PostBluesky