NeuroscienceThe EMBO JournalPeer-reviewed
Endo-lysosomal sorting and degradation of Tau mediates glucocorticoid-driven hippocampalmalfunction
João Vaz‐Silva, Patrícia Gomes, Qi Jin…·Clarissa L. Waites
This study shows that glucocorticoids impair Tau degradation via the Rab35/ESCRT pathway, leading to Tau accumulation and hippocampal dysfunction.
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