Author

Delphine Guillotin

University College LondonORCID 0000-0002-2464-6848Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Greg ContentoiD· 2 shared Jo-Anne A M WilsoniD· 2 shared Manuela PlatéiD· 2 shared Rachel Clare ChambersiD· 2 shared Alexander I. WardiD· 1 shared Brintha SelvarajahiD· 1 shared Katiuscia BianchiiD· 1 shared Madeleine RossaneseiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

Greg ContentoORCID

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2 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedSep 2, 2026

Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts

Jo-Anne A M Wilson, Rachel Walters, Greg Contento…·Rachel Clare Chambers

This study shows that the TGF-β1/mTORC1 signalling axis regulates the transcriptional identity of CTHRC1+ fibroblasts in IPF, supporting mTORC1 as a therapeutic target.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyJCI InsightPeer-reviewedAug 13, 2024

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

Greg Contento, Jo-Anne A M Wilson, Brintha Selvarajah…·Rachel Clare Chambers

This study shows that pyruvate metabolism affects fibroblast response to GLS1 inhibition during fibrosis, suggesting combined targeting of pyruvate metabolism and glutaminolysis as a therapeutic strategy.

23 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky