Author

Greg Contento

University College LondonORCID 0000-0002-2228-3123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Rachel Clare ChambersiD· 3 shared Delphine GuillotiniD· 2 shared Jo-Anne A M WilsoniD· 2 shared Manuela PlatéiD· 2 shared A. Reed· 1 shared Alexander I. WardiD· 1 shared Alison E. JohniD· 1 shared Bin LiuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Rachel Clare ChambersORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedSep 2, 2026

Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts

Jo-Anne A M Wilson, Rachel Walters, Greg Contento…·Rachel Clare Chambers

This study shows that the TGF-β1/mTORC1 signalling axis regulates the transcriptional identity of CTHRC1+ fibroblasts in IPF, supporting mTORC1 as a therapeutic target.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintJan 23, 2026

Targeting AKAP13 RhoGEF activity ameliorates pro-fibrotic phenotypes driven by the IPF associated AKAP13 risk variant

Bin Liu, James Michael May, Greg Contento…·Alison E. John

This study shows that an AKAP13 genetic variant promotes fibrosis by altering epithelial signaling, and inhibiting AKAP13's RhoGEF activity reduces fibrotic markers in IPF models.

DOI 10.64898/2026.01.21.700846

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyJCI InsightPeer-reviewedAug 13, 2024

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

Greg Contento, Jo-Anne A M Wilson, Brintha Selvarajah…·Rachel Clare Chambers

This study shows that pyruvate metabolism affects fibroblast response to GLS1 inhibition during fibrosis, suggesting combined targeting of pyruvate metabolism and glutaminolysis as a therapeutic strategy.

23 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky