Author

Julyan Arbel

Institut polytechnique de GrenobleORCID 0000-0002-2525-4416Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Assay:GWAS summary statistics· 3 Research Focus:polygenic risk· 3 Approach:statistical model· 3 Approach:Bayesian inference· 2 Approach:benchmark study· 2 Organism:human· 2 Research Focus:variant effect prediction· 2

Frequent Co-Authors

Bjarni Jóhann VilhjálmssoniD· 3 shared Florian PrivéiD· 3 shared Bogdan PaşaniuciD· 1 shared Clara AlbiñanaiD· 1 shared Hugues AschardiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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3 shared papersGenetics

Bjarni Jóhann VilhjálmssonORCID

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3 papers

Recent·Most cited

GeneticsThe American Journal of Human GeneticsPeer-reviewedNov 8, 2023

Inferring disease architecture and predictive ability with LDpred2-auto

Florian Privé, Clara Albiñana, Julyan Arbel…·Bjarni Jóhann Vilhjálmsson

This paper validates LDpred2-auto for inferring genetic parameters and shows improved heritability capture and predictive performance with an expanded variant set.

89 citationstop 1%

humanGWAS summary statistics

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GeneticsHuman Genetics and Genomics AdvancesPeer-reviewedAug 18, 2022

Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

Florian Privé, Julyan Arbel, Hugues Aschard, Bjarni Jóhann Vilhjálmsson

The paper identifies misspecifications in GWAS summary statistics and shows how to correct them to improve polygenic score predictive performance.

88 citationstop 1%

GWAS summary statisticsstatistical model

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GeneticsBioinformaticsPeer-reviewedDec 1, 2020

✦ In-depth digest

LDpred2: better, faster, stronger

Florian Privé, Julyan Arbel, Bjarni Jóhann Vilhjálmsson

LDpred2 reworks LDpred with a 3 cM LD window plus sparse and auto options, reaching mean AUC 65.1% over 8 real traits versus 63.8% for lassosum.

726 citationstop 1%

humanGWAS summary statistics

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