Junke Zhang

The paper develops a dual reporter assay to measure promoter and enhancer potential, finding that they share regulatory logic and can function reciprocally.

This paper introduces NetFlow3D, a framework that integrates protein structure and interaction networks to identify significant mutation clusters and modules in cancer, revealing biological processes not found by traditional methods.

This study shows that PGRN deficiency affects amyloid-beta levels and microglial activation in a sex- and age-dependent manner, influencing lysosomal activity and inflammation in Alzheimer's disease.