Author

Jessica D. Rosarda

Scripps Research InstituteORCID 0000-0002-2742-7413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

R. Luke WisemaniD· 2 shared Caroline R. StantoniD· 1 shared Emily B. Chen· 1 shared Evan T. PowersiD· 1 shared Michael J. BollongiD· 1 shared Nicole MadrazoiD· 1 shared Zinia KhattariD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

R. Luke WisemanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedMar 27, 2024

Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations

Nicole Madrazo, Zinia Khattar, Evan T. Powers…·R. Luke Wiseman

The paper identifies the integrated stress response (ISR) as the primary signaling pathway activated by mitochondrial proteostasis stress using gene set profiling in Perturb-seq datasets.

14 citations

humanscRNA-seq

𝕏 PostBluesky

Cell BiologyIsrael Journal of ChemistryPeer-reviewedNov 8, 2023

Pharmacologic Targeting of PDIA1 Inhibits NLRP3 Inflammasome Assembly and Activation

Jessica D. Rosarda, Caroline R. Stanton, Emily B. Chen…·R. Luke Wiseman

This study shows that AA147 inhibits NLRP3 inflammasome activity by covalently modifying PDIA1, suggesting PDIA1 as a therapeutic target for inflammatory diseases.

7 citations

humanproteomics

𝕏 PostBluesky