Matthew W. Lux

This paper develops a cell-free biosynthesis system for 1,2,4-butanetriol, achieving high productivity and yield at scale while reducing costs.

This paper develops a semi-automated method for manufacturing cell-free biosensors using liquid handling robotics, demonstrating comparable performance to manual methods.

This paper develops high-throughput methods to optimize cell-free biosensors on paper, achieving cost-effective and heat-tolerant formulations for field use.

This paper demonstrates that dried cell-free protein synthesis reactions can withstand harsh conditions during polymer casting, enabling the creation of functional materials with spatially patterned genetic capabilities.

This study develops a cell-free metabolic engineering platform to produce protoporphyrin IX, achieving 0.109 mg/mL yields through optimized buffer conditions and co-culturing techniques.

This paper describes a cost-effective and rapid method for characterizing genetic parts using cell-free lysates and high-throughput techniques.

barCoder generates unique genetic tags for qPCR detection, ensuring specificity and minimizing cross-reactivity with contaminants.

The paper shows lyophilized cell-free systems can tolerate organic solvents, enabling new applications like polymer-based delivery.

This paper investigates the use of silk fibroin as an additive in cell-free protein synthesis, finding it increases productivity but does not protect against drying and inhibits hydrogel formation.

The paper develops a method to characterize engineered T7-based transcription factors using cell-free protein synthesis and validates it through kinetic modeling.