Ana Leda F. Longhini

This study shows that SMARCA4 mutations in ovarian cancer increase immunogenicity through interferon response and epigenetic changes, enhancing T cell and NK cell activity in the tumor microenvironment.

This study shows that C57BL/6J, BALB/cJ, and J:ARC(S) mice develop persistent subclinical Chlamydia muridarum infections with immune responses, suggesting the need to exclude Cm from mouse colonies used in GI disease research.

This study shows that reducing hypothalamic somatostatinergic neurons in mice leads to diabetes-like symptoms in multiple tissues without hyperglycemia.