Andrew L. Paek

The paper shows that high H2O2 stress inhibits translation to prevent TF accumulation, while low H2O2 allows TFs like p53 and NRF2 to drive stress responses.

The paper shows that inducing quiescence in human RPE cells causes rapid DSB accumulation, leading to quiescence heterogeneity and requiring DSB repair for cell cycle re-entry.

This study uses high-throughput screens in human cells with authentic SARS-CoV-2 virus to identify neutralizing monoclonal antibodies and kinase inhibitors with minimal host toxicity.

The paper introduces a spatio-temporal deep neural network for cell lineage analysis in microscopy images, achieving high performance on multiple datasets.