Gaurav Sharma

This study investigates the evolutionary distribution of chemosensory systems in Actinomycetota, finding lineage-specific retention and expansion, with TCS playing a dominant role in regulatory networks.

The paper identifies the role of biosurfactant polysaccharide in regulating myxospore dispersal by reducing surface stickiness, while revealing the true outermost coat as exopolysaccharide.

The paper analyzes chemosensory systems across Vibrionales, identifying four types and revealing a conserved core and three accessory systems with distinct evolutionary patterns.

novelBGC assesses BGC novelty and prioritizes candidates using two scores, outperforming single-axis tools in identifying novel clusters.

This study examines the co-distribution of archaellum loci with chemosensory systems in archaea and monoderm bacteria, revealing horizontal gene transfer and shared evolutionary trajectories.

The paper introduces a comprehensive database integrating 16S, 23S, and 5S rRNA sequences, alignments, intragenomic heterogeneity, and secondary structures from around 5000 microbial genomes.

This study analyzes the distribution of Carbohydrate Active Enzymes (CAZymes) in 61 myxobacterial genomes to assess their potential for degrading lignocellulosic biomass and their ecological impact.

The paper compares two genome assemblies of the same Myxococcus xanthus strain, identifies sequence variations, and constructs a consensus circular genome, highlighting genomic diversity in a prophage region.

The paper identifies a new myxobacterial family, Pendulisporaceae, with unique biosynthetic gene clusters and potential pharmaceutical applications.

This paper shows that E. coli uses a small RNA, CpxQ, to regulate long-chain fatty acid metabolism and maintain redox homeostasis by suppressing LCFA processing and increasing ubiquinone levels.

This study uses genomic and bioinformatic analysis to classify five Streptomyces species from the Himalayas and identify their biosynthetic potential for antibiotic production.

This study sequenced and compared the genome of Priestia filamentosa JURBA-X, identifying its drought tolerance, plant growth promotion, and fluorescent properties linked to resistomycin production.

The paper identifies the origin of plasmid pMF1 in Myxococcus fulvus 124B02, showing it originated from a chromosomal segment of M. stipitatus, and confirms M. stipitatus CYD1 as a novel species.

The paper identifies CglD as a β-integrin-like adhesin in Myxococcus xanthus that stabilizes bacterial focal adhesions and enables gliding motility through mechanosensory and mechanotransductory functions.

The paper analyzes MPXV genomes and host-virus interactions to identify mutational hotspots, functional patterns, and potential drug repurposing targets for monkeypox treatment.

The paper tracks mutation frequency changes in 2,457 SARS-CoV-2 strains from India over seven months, identifying 19 variants with increasing or decreasing mutational probabilities.