Molecular BiologybioRxivPreprint
A CyclinB2-Cas9 fusion promotes the homology-directed repair of double-strand breaks
Manuel M. Vicente, Afonso Mendes, M. Jason de la Cruz…·Vasco M. Barreto
This paper describes a CyclinB2-Cas9 fusion protein that enhances homology-directed repair of double-strand breaks by promoting Cas9 activity during the G2 phase of the cell cycle.