An Q Dinh

The paper characterizes recalcitrant enterococcal bacteremia through clinical and genomic analysis, finding species-specific genetic adaptations in persistent infections.

The paper assesses how ESBL-positive ST131 E. coli adapts to carbapenem exposure, finding increased ESBL gene copy numbers and Omp gene mutations correlate with resistance development.

This study examines TBDR mutations in P. aeruginosa clinical isolates and their association with cefiderocol resistance and heteroresistance.

This study shows that ACL loss in the heart increases glucose oxidation and reduces citrate efflux, leading to metabolic remodeling and cardiac dysfunction.

This study identifies the MadRS system and its operon madEFG as mediators of resistance to antimicrobial peptides and antibiotics in Enterococcus faecalis, linking membrane lipid changes to stress response and virulence.

This study shows that D2-HG induces cachexia in mice by disrupting NAD+ homeostasis and autophagy, revealing metabolic vulnerabilities in skeletal muscle.