Author
University of WashingtonORCID 0000-0002-2999-899XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Anjali P. Patni, Rubul Mout, Rachel Moore…·Hannele Ruohola‐Baker
The paper demonstrates that a designed soluble Notch agonist can drive iAM maturation without odontoblast contact, revealing DLX3's role in ameloblast-specific Enamelin and MMP20 expression.
Ammar Alghadeer, Sesha Hanson-Drury, Devon Duron Ehnes…·Hannele Ruohola‐Baker
The paper establishes a single-cell atlas of human tooth development and uses it to guide the in vitro differentiation of ameloblasts from iPSCs, developing a mineralizing enamel organoid system.
Shiri Levy, Logeshwaran Somasundaram, Infencia Xavier Raj…·Hannele Ruohola‐Baker
The paper uses a computationally designed PRC2 inhibitor, EBdCas9, to identify functional TATA boxes in distal promoter regions and demonstrate their role in gene activation.