Author

J. G. F. Hoock

Technical University of DenmarkORCID 0000-0002-3037-3209Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Cecilia RossettiiD· 2 shared Laura DeptaiD· 2 shared Luca LaraiaiD· 2 shared Alison ForresteriD· 1 shared Daniel Gillet· 1 shared Georg E. WinteriD· 1 shared John C. ChristiansoniD· 1 shared Julien Barbier· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Cecilia RossettiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 1, 2023

Selective inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation

Nianzhe He, Laura Depta, Cecilia Rossetti…·Luca Laraia

This study identifies oxybipins, selective OSBP inhibitors, which block retrograde trafficking and reduce Shiga toxin toxicity by inducing Golgi degradation.

DOI 10.1101/2023.04.01.534865

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

Cell BiologyChemical SciencePeer-reviewedJan 1, 2023

Identification of non-conventional small molecule degraders and stabilizers of squalene synthase

J. G. F. Hoock, Cecilia Rossetti, Mesut Bilgin…·Luca Laraia

This study identifies small molecules that either degrade or stabilize squalene synthase, showing that degradation is possible despite challenges and providing a foundation for future probe development.

6 citations

proteomicsexperimental assay

𝕏 PostBluesky