Peng Liu

MPAC infers pathway activities from multi-omic data to identify patient subgroups and clinically relevant proteins, demonstrating improved results over single-omic analyses in head and neck cancer.

This study identifies Fpr2's role in immune homeostasis by regulating neutrophil subpopulations via CCL4 and Anxa1, revealing mechanisms of bacterial resistance.

The paper introduces SAT, a method that uses both paired and unpaired data to improve association tests between biomedical data types, showing better control of false discovery and increased power in real-world applications.