GenomicsGenome ResearchPeer-reviewed
Nascent RNA sequencing reveals a dynamic global transcriptional response at genes and enhancers to the natural medicinal compound celastrol
Noah Dukler, Gregory T. Booth, Yi-Fei Huang…·Adam C. Siepel
This study uses PRO-seq to analyze the rapid transcriptional response to celastrol in K562 cells, revealing two waves of transcriptional changes and identifying key transcription factors involved.
46 citations