Author

Uri Barenholz

Weizmann Institute of ScienceORCID 0000-0002-3097-9681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ron MiloiD· 2 shared Dan DavidiiD· 1 shared Ed ReznikiD· 1 shared Eran Segal· 1 shared Leeat Keren· 1 shared Niv AntonovskyiD· 1 shared Yinon M. Bar‐OniD· 1 shared Εlad NooriD· 1 shared

Activity by Year

2016-2017 · peak 1/yr

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8 top collaborators · 18 mutual co-author links

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2 shared papersSystems Biology

Ron MiloORCID

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2 papers

Recent·Most cited

Systems BiologyeLifePeer-reviewedFeb 7, 2017

Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points

Uri Barenholz, Dan Davidi, Ed Reznik…·Ron Milo

The paper shows that autocatalytic cycles in E. coli central carbon metabolism require specific enzyme expression and substrate affinity constraints to maintain stable fluxes.

89 citations

E. coliproteomics

𝕏 PostBluesky

Systems BiologyPLOS ONEPeer-reviewedApr 13, 2016

A minimalistic resource allocation model to explain ubiquitous increase in protein expression with growth rate

Uri Barenholz, Leeat Keren, Eran Segal, Ron Milo

The paper presents a minimalistic model explaining the coordinated increase in protein expression with growth rate, validated using E. coli proteomics data.

DOI 10.1371/journal.pone.0153344

E. coliproteomics

𝕏 PostBluesky