Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling
Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A. Glauser
Author
University of FribourgORCID 0000-0002-3228-7304Unclaimed ORCID profile · follow to get notified of new preprints
9 papers
Recent·Most cited
Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A. Glauser
Bolaji N. Lüthi, Jennifer I. Semple, Anja Haemmerli…·Peter Meister
The paper identifies cohesin-dependent 3D chromatin structures called fountains around active enhancers in C. elegans, showing their role in repressing enhancer activity and linking genome architecture to behavior.
Martina Rudgalvyte, Zehan Hu, Dieter Kressler…·Dominique A. Glauser
This study identifies CMK-1 and TAX-6/CnA as antagonistic regulators of thermo-nociceptive adaptation in C. elegans, acting in distinct neurons to modulate noxious heat avoidance behaviors.
Jonatan Kendler, Florian Wӧls, Saurabh Thapliyal…·Shi Yan
This study identifies AMAN-3 as a Golgi α-mannosidase essential for tri-fucosylation of nematode N-glycans, which affects growth and behavior in C. elegans.
Andrea Brenna, Micaela Borsa, Gabriella Sarò…·Urs Albrecht
This study shows that Cdk5 activity, modulated by light, gates rapid circadian phase shifts by regulating calcium influx and signaling pathways in SCN neurons.
Domenica Ippolito, Dominique A. Glauser
The paper identifies multiple calcium-dependent mechanisms regulating CMK-1 subcellular localization in C. elegans thermal nociceptors, showing how phosphorylation and CaM binding interact to control nuclear entry and export.
Saurabh Thapliyal, Isabel Beets, Dominique A. Glauser
The paper shows how C. elegans integrates food and temperature inputs through multisite gating in sensory circuits to control persistent behavioral states.
Georgina Gómez-Saldívar, Jaime Osuna-Luque, Jennifer I. Semple…·Peter Meister
The paper introduces RAPID, a method to determine tissue-specific transcriptional footprints in C. elegans without cell sorting, and validates it by identifying novel transcriptional profiles in rare cell types.
Jana P. Lim, Holger Fehlauer, Alakananda Das…·Miriam B. Goodman
The paper shows that CMK-1 in ASE neurons is essential for salt aversive learning in C. elegans by regulating calcium responses to salt.