Guilherme Meira Lima

The paper introduces two methods to profile functional glycan-lectin interactions in tissues using single-cell and spatial multiomic approaches, revealing stimulus-specific glycan remodeling and spatial glycan programs in immune cells and follicular lymphoma.

The paper introduces a universal baseline method to improve reproducibility in in vitro selection of genetically encoded libraries using NGS data.

The paper develops Siglec-liposomes to detect Siglec ligands and modulate immune cell function, showing they enhance T cell proliferation.

This paper evaluates the multiplexed liquid glycan array (LiGA) for detecting ABO blood group antibodies in human serum, identifying its strengths and limitations.

This paper develops a phage-based liquid lectin array to detect subtle glycocalyx differences by displaying multivalent lectins on DNA-barcoded M13 phage.

This paper introduces a method to measure glycan recognition profiles of lectins on live cells using a liquid glycan array (LiGA) platform and next-generation sequencing.

This paper develops a DNA-encoded method to display multivalent proteins on phage and demonstrates its use to study in vivo clearance rates of L-asparaginase.