Author

Ruifang Tian

University Medical Center GroningenORCID 0000-0002-3333-1944Unclaimed ORCID profile · follow to get notified of new preprints

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Ruifang Tian1 paper · University Medical Center Groningen

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Floris FoijeriD· 2 shared Maria F. Suárez Peredo RodrígueziD· 2 shared Petra L. BakkeriD· 2 shared René WardenaariD· 2 shared Siqi ZhengiD· 2 shared Stefano SantaguidaiD· 2 shared Anna Haider Rubio· 1 shared Anouk van den BrinkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Floris FoijerORCID

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2 papers

Recent·Most cited

Cancer BiologyThe EMBO JournalPeer-reviewedApr 13, 2026

Chromosomal instability promotes cell migration and invasion via EFEMP1 in extracellular vesicles

Siqi Zheng, Ruifang Tian, Marsudi Siburian…·Floris Foijer

This study shows that chromosomal instability in TNBC increases EV secretion and promotes cell migration via EFEMP1, identifying EFEMP1 as a potential therapeutic target.

DOI 10.1038/s44318-026-00766-4

humanbulk RNA-seq

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Cancer BiologyEMBO ReportsPeer-reviewedJan 21, 2025

CDC20 determines the sensitivity to spindle assembly checkpoint (SAC) inhibitors

Siqi Zheng, Linoy Raz, Lin Zhou…·Uri Ben‐David

The paper identifies CDC20 expression as a determinant of sensitivity to SAC inhibitors, showing that aneuploid cells with high CDC20 levels are more sensitive to these drugs.

10 citations

humanproteomics

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