Author
Medizinische Hochschule HannoverORCID 0000-0002-3365-6933Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Sereina O. Sutter, Kurt Tobler, Michael Seyffert…·Cornel Fraefel
The paper identifies IFI16 as a restriction factor for AAV2 transduction that acts independently of immune modulation by interfering with Sp1-dependent promoter activation.
Sereina O. Sutter, Sarah Jetzer, Anouk Lkharrazi…·Cornel Fraefel
The paper shows that inducing autophagy with hyperosmotic sucrose enhances AAV2 transduction efficiency through a non-canonical pathway, distinct from the PI3K-III-dependent mechanism.
Sereina O Sutter, Anouk Lkharrazi, Elisabeth M Schraner…·Cornel Fraefel
The paper investigates AAV2 uncoating and finds it occurs in a stepwise process completed in the nucleolus, with structural reorganization of the nucleolus supporting this process.