Author
University of AlbertaORCID 0000-0002-3372-4350Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Shayla R. Mosley, Natalie Lapa, Afshin Namdar…·Kristi Baker
The paper identifies cytosolic DNA structures in MSI CRC that enhance STING activation and anti-tumor immunity, suggesting potential for improved DNA-based therapies.
Chelsea E. Cunningham, Frederick S. Vizeacoumar, Yue Zhang…·Franco J. Vizeacoumar
The paper identifies synthetic dosage lethality targets for PLK1-overexpressing cancers using genome-wide screens and validates key hits to show their therapeutic potential.
Shayla R. Mosley, Angie Chen, David N.W. Doell…·Kristi Baker
The paper shows that genomic instability in MSI CRCs generates cytosolic DNA that enhances STING activation and anti-tumor immunity via dendritic cells, suggesting improved DNA-based therapies for CIN CRCs.