Systems BiologyMicrobiomePeer-reviewed
Regulation of blood-brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide
Lesley Hoyles, Matthew G. Pontifex, Ildefonso Rodríguez‐Ramiro…·Simon McArthur
This study shows that TMAO enhances BBB integrity and protects against inflammation, while TMA impairs BBB function and cognitive resilience in mice.
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