Marcel Schilling

SCALPEL quantifies single-cell transcript isoforms with higher sensitivity than existing tools, revealing novel cell populations and isoform regulation in mouse spermatogenesis and iPSC differentiation.

The paper identifies differentially expressed lncRNAs in Alzheimer's disease brains using RNA-seq data from multiple studies and brain regions.

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

This study identifies four novel DNA methylation loci in the entorhinal cortex associated with Alzheimer's disease and finds significant epigenetic age acceleration in patients.

The paper assesses differential microRNA expression in Parkinson's and Alzheimer's disease brains, identifying shared miRNAs with potential pathogenic roles.

The paper identifies differentially expressed miRNAs in two brain regions of Alzheimer's patients using qPCR and RNA-seq, highlighting potential targets involved in AD pathogenesis.

The paper maps RNA expression in C. elegans germline using cryo-cutting, identifies miRNAs and differential 3 UTR usage, and proposes regulatory mechanisms for spatial gene expression.