Author

Soňa Hubáčková

Czech Academy of SciencesORCID 0000-0002-3454-6840Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alena UvizliD· 1 shared Alexandra UrbancokovaiD· 1 shared Brian McStayiD· 1 shared Jiří BártekiD· 1 shared Josef F. NovakiD· 1 shared Martin MistríkiD· 1 shared Pavla VašicováiD· 1 shared Sarka Andrs SalajkovaiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alena UvizlORCID

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1 paper

Recent·Most cited

Cell BiologyeLifePeer-reviewedOct 25, 2023

Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment

Alexandra Urbancokova, Terezie Hornofova, Josef F. Novak…·Pavla Vašicová

This study shows that topological stress and RNAPI inhibition cause rDNA damage, leading to PML-nucleolar compartments (PNAs) that help prevent rDNA instability and may contribute to aging and cancer.

6 citations

humanDNA methylation

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