Cancer BiologyMolecular Cancer ResearchPeer-reviewed
ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3
Vernon Justice Ebegboni, Tamara L. Jones, Tayvia Brownmiller…·Natasha J. Caplen
This study identifies ETS1 as a target of the EWSR1::FLI1 fusion oncoprotein in Ewing sarcoma, showing it regulates TNS3 expression, which promotes cell movement and is linked to metastasis.
10 citations